pyridoxal phosphate

(redirected from pyridoxal 5-phosphate)
Also found in: Medical.

pyridoxal phosphate

(pĭr'ĭdŏks`əl): see coenzymecoenzyme
, any one of a group of relatively small organic molecules required for the catalytic function of certain enzymes. A coenzyme may either be attached by covalent bonds to a particular enzyme or exist freely in solution, but in either case it participates intimately in
..... Click the link for more information.
; vitaminvitamin,
group of organic substances that are required in the diet of humans and animals for normal growth, maintenance of life, and normal reproduction. Vitamins act as catalysts; very often either the vitamins themselves are coenzymes, or they form integral parts of coenzymes.
..... Click the link for more information.
.

pyridoxal phosphate

[‚pir·ə′däk·səl ′fä‚sfāt]
(biochemistry)
References in periodicals archive ?
The active site of the pyridoxal 5'-phosphate is in a fastened conformation because, the absence of pyridoxal 5-phosphate.
Pyridoxine is converted by all organs of the body to pyridoxal 5-phosphate (PLP) and pyridoxamine, which serve as coenzymes for transaminase reaction [13].
A randomized multicenter trial (N=214) found that adding a supplement containing L-methylfolate 3 mg, pyridoxal 5-phosphate 35 mg, and methylcobalamin 2 mg twice daily to other medications (eg, pregabalin, gabapentin, or duloxetine) improved symptoms of diabetic neuropathy.
As for B2 and B6, the most active forms are riboflavin 5-phosphate and pyridoxal 5-phosphate, respectively.
Optimisation and validation of a sensitive high-performance liquid chromatography assay for routine measurement of pyridoxal 5-phosphate in human plasma and red cells using pre-column semicarbazide derivatisation.
Purified serine racemase has a molecular weight of 37 kDa and requires pyridoxal 5-phosphate for its activity.
To be biologically active, pyridoxamine is first converted by the body to pyridoxal 5-phosphate (PLP).