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quinacrine

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quinacrine [′kwin·ə·krən]
(pharmacology)
C23H30ClN3O Formerly an important antimalarial drug but now used in the treatment of giardiasis, tapeworm infections, amebiasis, and a variety of other conditions.


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Doctors tested the drug among 107 patients with prion disease, who were assigned to a group that either took a 300-milligram dose of quinacrine daily or to another that did not take the treatment.
At this point the UCSF researchers are still recruiting patients to help them determine if quinacrine helps, does nothing, or even worsens human prion diseases, Dr.
From experiments with cell cultures, they found that both quinacrine (a malaria drug) and chlorpromazine (Thorazine, an antipsychotic agent) showed substantial anti-prion properties at concentrations that were safe in humans.
 
 
 
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