Quinoline


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quinoline

[′kwin·ə‚lēn]
(organic chemistry)
C9H7N Water-soluble, aromatic nitrogen compound; colorless, hygroscopic liquid; also soluble in alcohol, ether, and carbon disulfide; boils at 238°C; used in medicine and as a chemical intermediate. Also known as chinoline; leucoline; leukol.

Quinoline

 

(2,3-benzopyridine), a heterocyclic compound. Quinoline is a colorless liquid with a characteristic sweetish odor and a boiling point of 238°C.

It is poorly soluble in water and readily soluble in alcohol and ether. It is a weak base and with acids forms salts, such as C9H7N·HCl. With alkyl halides, it forms quinolinium tertiary salts. Quinoline is found in coal tar, from which it is extracted together with isoquinoline. Synthetic quinoline is obtained by the Skraup reaction (seeSKRAUP SYNTHESIS). Quinoline is used as a solvent for sulfur and phosphorus and in the decarboxylation of aromatic acids and other reactions. Many alkaloids, such as quinine and fagarine, and drugs, such as Atophan (cinchophen), Entero-Septol (iodochlorhydroxyquin), chloroquine, and primaquine, are derivatives of quinoline, as are several cyanine dyes and analytical reagents, such as 8-hydroxyquinoline.

References in periodicals archive ?
quinoline compounds) and novel compounds, where the identification of known compounds confirms the use of this approach as a tool for prioritizing compounds in follow-up studies.
Each Zn (II) centre is thus coordinated to an oxygen atom from each of two sulphate bridges, a chlorine atom and quinoline atom N(4) of the quinine moiety.
On the hitlist are: colours Quinoline Yellow (E104), Sunset Yellow (E110), Cormoisine (E122), Ponceau 4R (E124), Alluro Red (E129) and preservative sodium benzoate (E211)
The colourings are sunset yellow (E110), tartrazine (E102), carmoisine (E122), ponceau 4R (E124) and sodium benzoate (E110); then sunset yellow (E110), quinoline yellow (E104), carmoisine (E122), allura red (E129) and sodium benzoate (E110).
Dolly mixture sweets and flying saucers are among the children's products which have been reformulated to remove colourings such as Quinoline Yellow (E104), Cochineal (E120), and Indigo Carmine (E132).
Colourings to avoid in kids' food and drink: E102 Tartrazine; E104 Quinoline Yellow; E107 Yellow 2G; E110 Sunset Yellow; E120 Cochineal; E122 Carmoisine; E123 Amaranth; E124 Ponceau 4R; E127 Erthrosine; E128 Red 2G; E129 Allura Red; E131 Patent Blue V; E132 Indigo Carmine; E133 Brilliant Blue FCF; E142 Green S; E151 Black PN; E154 Brown FK; E154 Brown HT .
Finally, in the case of the quinoline compound, the rate of photo-deprotection was 10-fold slower than that for the corresponding unsubstituted indoline.
This index with the dimension [[degrees]C/min], with its value usually about 100, is obtained as a derivative of the dependence of increasing temperature T [[degrees]C] of a coal briquette on time [tau] [min] at T = 232 [degrees]C corresponding to the boiling point of quinoline.
Wicked Orange" sauce, still made from tomatoes and tasting the same as the original, contains quinoline which Food Commission chief Tim Lobstein said some children may react to.
The organic dye degraded is quinoline acid yellow (QAY) obtained from Aldrich Chemical Company.
The firstly reported natural non-terpenoid quinoline alkaloids, such as 6-methoxykynurenic acid 1, kynurenic acid 2 and 6-hydroxykynurenic acid 3 (Michael 1998), can be isolated from higher plant Ephedra pachyclada (Fig.