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racemate

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racemate

Mixture of equal quantities of two enantiomers, substances whose molecular structures are mirror images of one another (see isomer). The two enantiomers rotate polarized light through opposite angles, canceling each other out so that the racemic mixture has no optical activity. Racemization is the conversion of an optically active form of a compound into a racemic mixture; reversing this process is called resolution.


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Because it's difficult to predict just how a racemate will affect people, pests, or the environment, most chemists would prefer to avoid such mixtures.
Supported by the FDA's 1992 Stereoisomeric Drug Development Policy, L-leucovorin theoretically is the preferred therapeutic enantiomer when compared with the marketed racemate (d,l-leucovorin) in the US.
 
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