racemate

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Related to racemates: racemic modification

racemate

[′ras·ə‚māt]
(organic chemistry)
An equimolar mixture of the two enantiomers (+ and -, or R and S) of a substance; it is optically inactive.
References in periodicals archive ?
The fact that enantiomers often do have benefits over racemates motivates scientists to try new ones to see if they confer such a benefit, just as the fact that a general area that is known to contain gold will motivate a search even though no one knows whether a particular plot of land will contain gold or not.
Figure 8 shows the examples of the racemates resolved on the PTrMA column.
Ultrafiltration experiments were conducted to evaluate the chiral separation ability of the prepared membrane towards racemate aqueous solution of Phenylalanine.
The chiral switch: the development of single enantiomer drugs from racemates.
The reason that the CHMP determined that eszoplicone should not be granted new active substance status was because Sepracor failed to prove relevant and clinically meaningful differences between eszopiclone and the racemate of which it was the active enantiomer, zopiclone in an adequate planned clinical trial with direct head to head comparison.
151) On separation, it was found that none of the separated enantiomers afforded any benefit over their respective racemates and the Sanofi scientists concluded that the resolution of enantiomers within that structural class was futile.
In India, major therapeutic advances are rare and some products are mere stereoisomers of already existing molecules, few of which offer substantial advantages over racemates that have long been available (30).
Lipase-mediated chiral resolution of racemates in organic solvents.
In the current study, his lab found (using an HPLC column containing a specific molecule that can "discriminate" between the L- and D-forms) that all of the ingredients ostensibly labeled as the L- isomer were indeed racemates, comprised of nearly 50-50 mixtures of L- and D-theanine enantiomers.
This is particularly important in view of the fact that many drugs are chiral and are synthesized as racemates, while only one of the enantiomers is of pharmaceutical interest.