regulatory sequence


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regulatory sequence

[′reg·yə·lə‚tȯr·ē ‚sē·kwəns]
(cell and molecular biology)
A sequence of deoxyribonucleic acid to which gene regulatory proteins bind to control the rate of transcription.
References in periodicals archive ?
This result indicates that when the [beta]-casein gene is knocked-out by gene targeting and a specific foreign gene is inserted in its place, the foreign gene can be expressed by the [beta]-casein gene regulatory sequence.
Further for the analysis of the pattern of regulatory sequence of coexpressed virulence genes, by using RSAT program, first we mine their upstream region, then oligo-analysis and dyad-analysis was performed (van-Helden et al.
Natural haplotypes in the regulatory sequences affect human alcohol dehydrogenase 1C (ADH1C) gene expression.
Remember that Accord was inserted into the regulatory sequence of the Cyp6g1 in resistant fruitflies.
They found that many people now living in Europe and eastern Africa possess three copies of the prodynorphin regulatory sequence, whereas people in India and China usually possess two copies of that sequence.
However, a preceding transcription regulatory sequence, 5'-UCCAAAC-3', can be identified upstream of the envelope protein in DcCoV UAE-HKU23, as in other betacoronavirus A1 members (Table 3; online Technical Appendix Table 1) (19,30).
A regulatory sequence is a region of DNA associated with a gene that influences the expression of that gene.
Patent 5,830,686 claims a human prostate-specific transcriptional regulatory sequence, the polynucleotides that comprise such regions, the toxin gene that is controlled by the regulatory sequence, and methods for treating prostate disease using toxin gene constructs.
Transcription factors are proteins which bind to a regulatory sequence of a gene in order to activate the gene.
These technologies can help to unweave the complex network of functional interactions within the spliceosome and of the spliceosome with regulatory factors, exhaustively map the contribution of regulatory sequences and be used to investigate, with unprecedented detail, mechanisms of regulation for essentially any regulator or alternative splicing event operating in a particular cell line.
We looked inside the shared regulatory sequences and found mouse and human genomes to have a common language in regulation, but that there is a tremendous amount of flexibility in evolution.