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regulatory sequence

   Also found in: Medical, Wikipedia 0.01 sec.
regulatory sequence [′reg·yə·lə‚tȯr·ē ‚sē·kwəns]
(cell and molecular biology)
A sequence of deoxyribonucleic acid to which gene regulatory proteins bind to control the rate of transcription.


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In many cases, she says, the mutation of one regulatory sequence of the SHOX gene is sufficient to give rise to the full-blown syndrome.
The exact mechanism of how increased expression of Cyp6g1 occurs in DDT-resistant fruitflies is unknown at this stage, but Daborn and colleagues showed that a transposable element (sometimes known as a 'jumping gene') called Accord is inserted into the Cyp6g1 regulatory sequence (the DNA sequences in front of a gene, controlling its expression).
Changes, or mutations, in the human prodynorphin regulatory sequence must have enhanced survival over other primate species, the investigators contend, while the geographic differences that they found may have bestowed as yet unknown advantages on specific human populations.
 
 
 
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