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renin |
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renin [′rēn·ən] (biochemistry) A proteolytic enzyme produced in the afferent glomerular arteriole which reacts with the plasma component hypertensinogen to produce angiotensin II. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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In animal studies, in utera and postnatal exposure to 100 ppm lead in drinking water increased blood pressure, but exposure to 5 or 25 ppm did not, although renin activity was increased to 25 ppm (Victery et al. For instance, studies suggest that part of the reason for the disparities in rates of heart disease may be differences in how African Americans process salt and use renin, an enzyme secreted by the kidneys, resulting in high rates of hypertension. 23,33) Most people in this stage are hypertensive secondary to increased production of renin. |
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