Also found in: Dictionary, Thesaurus, Medical, Wikipedia.


see rennetrennet,
substance containing rennin, an enzyme having the property of clotting, or curdling, milk. It is used in the making of cheese and junket. Rennet is obtained from the stomachs of young mammals living on milk, especially from the inner lining of the fourth, or true,
..... Click the link for more information.



(also chymosin), a proteolytic enzyme produced by the mucous membrane of the abomasum, or fourth stomach, of young ruminants. Rennin, in the form of abomasal extract, has long been used for coagulating milk in cheese-making. It is synthesized as an inactive precursor, renninogen, which is converted into rennin in an acid medium at pH < 5.0. The starting substrate for rennin is the milk protein κ-casein, which under the action of rennin loses the ability to stabilize the casein micelles. Rennin is obtained in crystalline form; its molecule is composed of a polypeptide chain (molecular weight ~ 34,000) in which dicarboxylic amino acids predominate. Rennin resembles pepsin in many of its properties.


An enzyme found in the gastric juice of the fourth stomach of calfs; used for coagulating milk casein in cheesemaking. Also known as chymosin.
References in periodicals archive ?
Congenital mesoblastic nephroma, rennin production, and hypertension.
The reduction was associated with decrease in systemic vascular resistance, plasma norepinephrine, plasma rennin activity, body weight, waist size, per cent body fat and insulin resistance.
East Hanover, NJ, announced the FDA has approved Tekamlo (aliskiren and amlodipine) tablets, a single-pill for the treatment of high blood pressure combining the only approved direct rennin inhibitor, Tekturna (aliskiren), with the widely used calcium channel blocker amlodipine.
Compared with the control group, those assigned to nattokinase had a statistically significant decline in plasma rennin levels, which might account for the decline in BP.
Another mechanism is that the posts exercise hypotension which is accompanied by a decrease in serum catecholamine's, norepinephrine, dopamine, cortisol, sympathetic nervous system, plasma rennin activity thus suppresses inflammatory reaction and finally down-regulates WBC count.
In addition to this, BNP also inhibits rennin and aldosterone production, thus affecting the rennin-angiotensin system.
Rennin is an enzyme usually obtained from the stomach of a young calf in the brine solution called rennet.
Application of Radioimmunoassay for angiotensin I to the physiologic measurements of plasma rennin activity in normal subjects.
1980) Plasma AVP, neurophysin, rennin activity, and aldosterone during sub-maximal exercise performed until exhaustion in trained and untrained men.