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replacement study

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replacement study [ri′plās·mənt ‚stəd·ē]
(industrial engineering)
An economic analysis involving the comparison of an existing facility and a proposed replacement facility.
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Although it is commonly understood that postmenopausal women, particularly those with early menopause, have an increased risk of developing coronary artery disease and it was thought that hormone replacement therapy (HRT) would help to remedy this, some well-known clinical investigations, such as the Heart and Estrogen/progestin Replacement Study (HERS), were unable to demonstrate an improved outcome in postmenopausal women using HRT," said Dr.
Hormone replacement therapy 'beneficial for postmenopausal women' by Asian News International
The Heart and Estrogen/progestin Replacement Study (HERS) Research Group (I and later II) studies in women who had known preexisting cardiovascular disease initially raised questions about the increase in heart attacks in the first year of hormone therapy use, but it was the publication of the WHI few years later that raised the alarm.
Menopause and hormone therapy--how confused are you? by Thomas, Carol / CME: Your SA Journal of CPD
The first clinical trial to address the connection between HT hormone use and heart health was the Heart and Estrogen/ Progestin Replacement Study (HERS), which looked at whether the estrogen/progestin combination Prempro would reduce second heart attacks or cardiac death in women with established coronary artery disease.
Does the timing of menopause hormone therapy really matter when it ... by Raymond, Jonathan; Pearson, Cindy / Women's Health Activist
 
 
 
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