restriction point


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restriction point

[ri′strik·shən ‚pȯint]
(cell and molecular biology)
In the mammalian cell cycle, a time late in the G1 phase at which the cell commits to the replication of its deoxyribonucleic acid (DNA).
References in periodicals archive ?
The compound we identified forces the catastrophic failure of the normal virus amplification cycle and illustrates a new drug-accessible restriction point for poxviruses in general," said John Connor, PhD, assistant professor of microbiology at BUSM.
It is far easier to create a spot restriction in the sprue and carefully monitor pouring time to detect erosion of this restriction point.
Cycle regulation was introduced, with the major proliferation control located at the restriction point in late G1.