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retinoid receptor

   Also found in: Wikipedia 0.01 sec.
retinoid receptor [′ret·ən‚ȯid ri‚sep·tər]
(cell and molecular biology)
Any member of a family of nuclear receptors that mediate the actions of natural and synthetic analogs of vitamin A (retinoids) by regulating the transcription of retinoid-responsive genes in the cell nucleus.


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According to Zoe Diana Draelos, a dermatologist in High Point, NC, retinoids are so effective because skin cells have retinoid receptors on their surface.
Alitretinoin is the only retinoid that is known to act on both types of retinoid receptor, and for this reason it is sometimes described as a (retinoid) panagonist.
Meanwhile, 9-cis-retinoic acid (9-cis-RA) can bind another series of retinoid receptors, termed retinoid X receptors (RXR), and initiate transcription of RXR responsive genes in a ligand-dependent fashion (discussed by Rohde et al.
 
 
 
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