rheumatoid factor

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Related to rheumatoid factors: RF test

rheumatoid factor

[′rü·mə‚tȯid ‚fak·tər]
(immunology)
The immunoglobulin in the class IgM that is detected in the synovial fluid of individuals with rheumatoid arthritis.
References in periodicals archive ?
Rheumatoid factor was present in people aged 15-69 years and absent beyond 69 years.
We tested the hypothesis that increased concentrations of rheumatoid factor are associated with increased risk of deep venous thrombosis in individuals without autoimmune rheumatic disease in the general population.
Table 1 Comparison of Immune Complex Formation in the Autoimmune Diseases Rheumatoid Arthritis (RA) and Systemic Lupus Erythematosus (SLE) Immune response RA SLE Diagnostic RA cell (phagocytes LE cell (phagocytes tell-tale cell with ingested with ingested cell rheumatoid factor nuclei) complexes) Antigen Hinge region of IgG DNA, histones, etc.
Rheumatoid factor was first mentioned in 1958 in the Association of American Rheumatism (ARA) evaluation criteria.
Chronic inflammation of the hypertrophic synovium, on the other hand, is maintained by clusters of activated lymphocytes, mononuclear cells, and islands of plasma cells that make IgG and IgM rheumatoid factors directed against altered IgG.
Rheumatoid factor (RF) is currently the most accepted laboratory test for rheumatoid arthritis (RA) and is part of the revised American College of Rheumatology (ACR) classification criteria for RA (1).
coli K100 and Haemophilus influenzae type b, are known to frequently use the same V region genes that are present in human antibodies with autoimmune activity, including some rheumatoid factors (23, 24).
In laboratory examination, erythrocyte sedimentation rate (ESR) was 71mm/hr, C reactive protein (CRP) was 30mg/L, rheumatoid factor was 412 IU/ml, anti-CCP (cyclic citrullinated peptide) was positive.