Also found in: Dictionary, Thesaurus, Medical, Acronyms, Wikipedia.


see coenzymecoenzyme
, any one of a group of relatively small organic molecules required for the catalytic function of certain enzymes. A coenzyme may either be attached by covalent bonds to a particular enzyme or exist freely in solution, but in either case it participates intimately in
..... Click the link for more information.
; vitaminvitamin,
group of organic substances that are required in the diet of humans and animals for normal growth, maintenance of life, and normal reproduction. Vitamins act as catalysts; very often either the vitamins themselves are coenzymes, or they form integral parts of coenzymes.
..... Click the link for more information.



(also lactoflavin and Vitamin B2), an important and biologically active substance that is a derivative of the heterocyclic compound isoalloxazine attached to ribitol, a multi-atomic alcohol.

Riboflavin is widely distributed in the cells of microorganisms, plants, and animals, although animals are unable to bio-synthesize riboflavin and must obtain it with food. The biological role of riboflavin is determined by the presence of its derivatives—flavin mononucleotide (FMN) and flavin-adenine dinucleotide (FAD)—in a series of oxidation and reducing enzymes (flavoproteins) during electron transfer reactions and the metabolism of amino acids and other vitamins.

In man, many diseases are accompanied by disorders of the metabolism of riboflavin. A deficiency of riboflavin results in skin lesions and vision disorders, while an acute insufficiency leads to the development of a comatose state. Riboflavin is present in most food products, including brewer’s yeast, egg yolk, beef liver, and milk products. It is also synthesized by intestinal bacteria.

The structure of riboflavin was independently established in 1935 through chemical synthesis both by R. Kuhn and P. Karrer. Riboflavin is used in medicine as a vitamin preparation.


Vitaminy. Moscow, 1974. Chapter 8.


C17H20N4O6 A water-soluble, yellow orange fluorescent pigment that is essential to human nutrition as a component of the coenzymes flavin mononucleotide and flavin adenine dinucleotide. Also known as lactoflavin; vitamin B2; vitamin G.


, riboflavine
a yellow water-soluble vitamin of the B complex that occurs in green vegetables, germinating seeds, and in milk, fish, egg yolk, liver, and kidney. It is essential for the carbohydrate metabolism of cells. It is used as a permitted food colour, yellow or orange-yellow (E101). Formula: C17H20N4O6
References in periodicals archive ?
The test results clearly indicated that the weir-style valve bodies consistently showed riboflavin residue, while the Swagelok DR series radial diaphragm valves regularly exhibited no or very little residue.
Riboflavin (vitamin B2) is a heterocyclic mixture derived from an isoallosazine molecule linked with a ribitol chain that is required in many cellular processes.
8 mmol/L AA + 30 [micro]mol/L riboflavin and exposed to ambient light for 24 h at room temperature.
Outside the US, Avedro has obtained CE Mark for its KXL System for performing accelerated corneal cross-linking and for its family of riboflavin products.
2] vitamers in 9 different lots of plasma enriched with 30 nmol/L each of PN, PNP, PL, PM, riboflavin, and FMN and 150 nmol/L each of PLP, PMP, PA, and FAD after the protein precipitation step.
Avedro's research has made possible several technical breakthroughs that have been incorporated into our accelerated cross-linking devices and our family of proprietary riboflavin formulations," said David Muller, President and CEO of Avedro, "which together significantly increase the speed, precision, safety and efficiency of corneal collagen cross-linking.
We have had several discussions since then about riboflavin for migraines and about the difficult time he has had in trying to interest various medical doctors in this simple, safe, and inexpensive treatment.
DALLAS, March 16, 2015 /PRNewswire-iReach/ -- The 'Global and Chinese Riboflavin Industry, 2009-2019 Market Research Report' is a professional and in-depth study on the current state of the global Riboflavin industry with a focus on the Chinese market.
As noted above, riboflavin is a component of FAD, and it has been shown that individuals with the MTHFR 677TT genotype develop hyperhomocysteinemia only if they have poor riboflavin status.
5 The fruit is a good source of minerals such as copper, iron, potassium, manganese and magnesium as well as B-complex vitamins such as folates, riboflavin and pyridoxine.
The vitamin riboflavin is used for what purpose in food manufacture?
High Vitamin D Mushroom Powder provides vitamin D2 as well as viable levels of riboflavin, niacin, copper, beta-glucans, chitan-glucan, and is an excellent source of the antioxidant er-gothioneine.