(redirected from sarcolemmal)
Also found in: Dictionary, Thesaurus, Medical.


The thin connective tissue sheath enveloping a muscle fiber.



the delicate membrane that invests smooth-muscle cells and striated and myocardial fibers. The term “sar-colemma” was introduced by the British physician W. Bowman in 1840. A sarcolemma consists of a three-layer cell membrane, which is approximately 75 angstroms thick and similar to the cell membrane in other animal cells, and a basilar membrane, which is a layer of amorphous matter containing polysaccharides. In vertebrates the basilar membrane of muscle cells and muscle fibers usually contains collagen fibrils.


De Robertis, E., W. Nowinski, and F. Saez. Biologiia kletki. Moscow, 1967. (Translated from English.)
Elektronno-mikroskopicheskaia anatomiia. Moscow, 1967. (Translated from English.)
References in periodicals archive ?
The subsequent ROS sensitization of ryanodine receptors and sarcolemmal calcium influx channels increases myoplasmic calcium concentration and contraction leading to more stretch.
Redox modification of sodium calcium exchange activity in cardiac sarcolemmal vesicles J.
He wrote the chapter "Cardiac Sarcolemmal ATP-Sensitive Potassium Channel Antagonists" in Drug Discovery Handbook (Wiley).
The intrinsic forward rate constants for DHP binding to sarcolemmal calcium channel receptors were apparently not strongly dependent on their membrane partition coefficients.
16) These include free radical formation and lipid peroxidation resulting in mitochondrial, lysosomal and sarcolemmal membrane damage and a number of surface transferrin receptors in the cell and the ability of the cell to protect itself against inorganic iron.
Lactate transport studied in sarcolemmal giant vesicles from human muscle biopsies: Relation to training status.
Skeletal muscle damage is characterized by misaligned Z-discs and a disruption of the cell and sarcolemmal membrane (Clarkson and Hubal, 2002; Clarkson and Sayer, 1999; Ebbeling and Clarkson, 1989; Koch, 2008; Sayers and Clarkson, 2001).
2+] passively leaking through RYR1 and increased basal sarcolemmal [Ca.
The normal controls stained with IHC for dystrophin and b-spectrin showed positive stain of the sarcolemmal membrane (Fig.
Muscle tissues had small, focal areas of sarcoplasm degeneration, hyalinization or lysis, with mild to moderate proliferation of sarcolemmal nuclei (Fig.