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scrapie |
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scrapie: see prion prion diseases or transmissible spongiform encephalopathies. Well-known prion diseases are Creutzfeldt-Jakob disease (CJD) and kuru in humans, scrapie in sheep, bovine spongiform encephalopathy (BSE), also called "mad cow disease," in cattle, and chronic wasting disease in deer and ..... Click the link for more information. . scrapie [′skrā·pē] (veterinary medicine) A transmissible, usually fatal, virus disease of sheep, characterized by degeneration of the central nervous system. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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This observation sustains the idea that the involved agent could belong to a particular scrapie agent group that cannot be directly identified by using the current biochemical criteria for TSE agent discrimination. The assumption among those concerned is that some change or mutation in the scrapie agent permitted it to infect cattle, and this modified agent has potential to cross other species barriers. Detection of proteinase K-resistant prion protein and infectivity in mouse spleen by 2 weeks after scrapie agent inoculation. |
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