semiconservative replication

(redirected from Semiconservative)
Also found in: Dictionary, Medical.
Related to Semiconservative: semiconservative replication

semiconservative replication

[¦sem·i·kən′sər·vəd·iv rep·li′kā·shən]
(cell and molecular biology)
Replication of deoxyribonucleic acid by longitudinal separation of the two complementary strands of the molecule, each being conserved and acting as a template for synthesis of a new complementary strand.
References in periodicals archive ?
Temperature is considered to be a semiconservative tracer and is often used to infer the extent of mixing between diffuse flow and ambient seawater, which is then used to assume the chemical environment (Johnson et al.
1958 Matthew Meselson, Frank Stahl Used isotopes of nitrogen to prove the semiconservative replication of DNA.
Indeed, even with an immediate insight into how DNA might replicate, it was 5 years (1958) until the beautiful Meselson and Stahl experiment (Meselson and Stahl 1958) demonstrated semiconservative DNA replication, as predicted by Watson and Crick.