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sequencing |
Also found in: Dictionary/thesaurus, Medical, Wikipedia, Hutchinson | 0.01 sec. |
sequencingDetermining of the order of amino acids in a protein or of nucleotides in a nucleic acid or gene. The results have increased understanding of the mechanisms of life processes and have numerous applications. Whereas Frederick Sanger required 10 years to determine the structure and sequence of amino acids in insulin and about as long to determine the sequence of nucleotides in the DNA of a small virus, automated laboratory instruments and techniques can now do either task in days or hours. See also genetic code; polymerase chain reaction. |
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In what some scientists are describing as the most sweeping innovation in gene sequencing in the past 25 years, researchers have developed a tool that can read out DNA's genetic letters up to 100 times as fast as the standard technique does. It is anticipated that emerging technologies are sufficiently advanced that, with additional investment, it may be possible to achieve proof of principle or even early stage commercialization for genome-scale sequencing within five years. Two sets of meningococcal isolates were used for porA gene sequencing in this work. |
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