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Serology |
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Serology The division of biological science concerned with antigen-antibody reactions in serum. It properly encompasses any of these reactions, but is often used in a limited sense to denote laboratory diagnostic tests, especially for syphilis. The techniques of blood grouping have come from the study of antigen-antibody reactions in serum, as have techniques for identification of genetic polymorphism and quantitation of numerous serum proteins. With these advances came the means for developing transfusion therapy with cells and plasma. In addition, these techniques led to identification of antibodies involved in incompatibility reactions, such as in erythroblastosis fetalis, and the development of effective measures to prevent their occurrence. Further, extension of these techniques to identification of antigens on white cells led to effective methods of histocompatibility typing, facilitating organ transplantation. See Transplantation biology How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| For example, in the true account of a modern murder mystery, a serologist determined that a blood specimen that was submerged for 3 years in salt water was human blood. Serologist Fred Zain, a West Virginia state trooper and later chief serologist in the Bexar County (Texas) Medical Examiner's office, indicted for perjury for falsifying results used to convict several wrongly imprisoned defendants. In other types of major crime cases, investigators employ such specialists as pathologists, serologists, psychiatrists, fingerprint and document examiners, and criminalists to aid in analyzing evidence. |
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