Inhibitor

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Related to Serpin: Serine protease inhibitor, Serine proteinase inhibitors

inhibitor

[in′hib·əd·ər]
(aerospace engineering)
A substance bonded, taped, or dip-dried onto a solid propellant to restrict the burning surface and to give direction to the burning process.
(chemistry)
A substance which is capable of stopping or retarding a chemical reaction; to be technically useful, it must be effective in low concentration.

Inhibitor

 

a circuit having m + n inputs and a single output, at which a signal can appear only when there are no signals on the m inputs (inhibiting). The other n inputs (principal) form one of the two logic connections, “AND” or “OR.” Inhibitors are used extensively in computers. They are very often understood to be a circuit having a single principal input and a single inhibiting input. A signal appears at the output of such a circuit when a signal is present on the principal input but there is none on the inhibiting input. Such an inhibitor is called an anticoincidence gate; its conventional representation is given in Figure 1.

Figure 1. Block diagram of an anticoincidence gate (inhibitor) with m — 1 and n 1:(A) principal input, (Q) inhibiting input, (Ga) anticoincidence gate

inhibitor

A substance added to paint to retard drying, skinning, mildew growth, etc. Also see corrosion inhibitor, inhibiting pigment, drying inhibitor.
References in periodicals archive ?
Not unexpectedly, in light of nature's preoccupation with complementarity and contrariety, serpins also perform diverse nonproteolytic functions, including hormone carriage proteins (thyroxine-binding globulin, cortisol-binding globulin), tumor suppressor genes (maspin), and storage (ovalbumin, in egg white).
Characterization and functional analysis of Serp3: a novel myxoma virus-encoded serpin involved in virulence.
Patterns of haplotype diversity within the serpin gene cluster at 14q32.
5] Nonstandard abbreviations: A1AT, [alpha]-1-antitrypsin; SERPIN, serine protease inhibitor; COPD, chronic obstructive pulmonary disease; IEF, isoelectric focusing; MS, mass spectrometry; LC-MS/MS, liquid chromatography-tandem MS; TFE, trifluoroethanol; IAA, iodoacetamide; TFA, trifluoroacetic acid; DTT, dithiothreitol; FCS, fetal calf serum; Z 3-16, Zwittergent detergent 3-16; DMF, dimethylformamide; LOQ, limit of quantitation; MRM, multiple reaction monitoring.
Their paper, entitled "Antiangiogenesis: A novel activity for the cleaved conformation of the serpin antithrombin III," states results of Drs.
The grant entitled "A Novel Recombinant Serpin for the Treatment of Stroke" will provide funds for the continued development of the company's most advanced serine protease inhibitor, LEX 032, for the treatment of reperfusion injury.
In contrast, other serpin-serine protease interactions were not affected (PAI is a serpin, a class of protease inhibitors that includes a1-antitrypsin, a2-antiplasmin and antithrombin III).
alpha1-Antitrypsin Portland, a bioengineered serpin highly selective for furin: application as an antipathogenic agent.
Subsequently, more than 190 different mutations of the gene that encodes C1-INH, serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 (SERPINGI ), have been described (5).