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immunodeficiency
(redirected from severe combined immunodeficiency)

   Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.02 sec.

immunodeficiency

Defect in immunity that impairs the body's ability to resist infection. The immune system may fail to function for many reasons. Immune disorders caused by a genetic defect are usually evident early in life. Others can be acquired at any age through infections (e.g., AIDS) or immunosuppression. Aspects of the immune response that may be affected include lymphocytes, other leukocytes, antibodies, and complement. Severe combined immunodeficiency (SCID), which arises from several different genetic defects, disrupts all of these. Depending on the cause, treatment for immunodeficiency may be administration of immunoglobulins, bone-marrow transplant, or therapy for the underlying disease.


immunodeficiency
a deficiency in or breakdown of a person's immune system

immunodeficiency [¦im·yə‚nō·də′fish·ən·sē]
(immunology)
Any defect of antibody function or cell-mediated immunity.


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Jamie was born with severe combined immunodeficiency, so he effectively had no immune system.
Amid a tightening of regulatory oversight, gene therapy has only recently yielded what appears to be its first cures, reviving the immune systems of children with severe combined immunodeficiency, or SCID.
While there she met the parents of six-month-old Melody Davies who has undergone a bone marrow transplant after being diagnosed with rare Severe Combined Immunodeficiency.
 
 
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severe combined immune deficiency disease (SCID) (syndrome)
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