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immunodeficiency
(redirected from severe combined immunodeficiency disease)

   Also found in: Dictionary/thesaurus, Medical, Legal, Acronyms, Wikipedia 0.01 sec.

immunodeficiency

Defect in immunity that impairs the body's ability to resist infection. The immune system may fail to function for many reasons. Immune disorders caused by a genetic defect are usually evident early in life. Others can be acquired at any age through infections (e.g., AIDS) or immunosuppression. Aspects of the immune response that may be affected include lymphocytes, other leukocytes, antibodies, and complement. Severe combined immunodeficiency (SCID), which arises from several different genetic defects, disrupts all of these. Depending on the cause, treatment for immunodeficiency may be administration of immunoglobulins, bone-marrow transplant, or therapy for the underlying disease.


immunodeficiency
a deficiency in or breakdown of a person's immune system

immunodeficiency [¦im·yə‚nō·də′fish·ən·sē]
(immunology)
Any defect of antibody function or cell-mediated immunity.


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The strategy should work to treat hemophilia, thalassemia and severe combined immunodeficiency disease (the so-called bubble boy disease), Daley said.
Three products are currently marketed which utilize Enzon's technology: PEG-INTRON marketed by Schering-Plough for hepatitis C, ONCASPAR(R) for Acute Lymphoblastic Leukemia (ALL), and ADAGEN(R) a treatment for a form of Severe Combined Immunodeficiency Disease (SCID), commonly known as the "Bubble Boy Disease.
Both fetuses were found to have a condition known as severe combined immunodeficiency disease (SCID), in which the fetal immune system does not develop enough of certain infection-fighting cells known as T-cells, according to Evans.
 
 
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