Granulosa cell tumors arise from ovarian sex cords
and make up an estimated 1% of all ovarian cancer cases but comprise more than 70% of all sex cord
2] They encompass a heterogenous group of neoplasms containing variety of cells which are derived from gonadal sex cords or stromal cells.
They are carcinosarcomas of the ovary, sex cord stromal tumours, germ cell tumours, small cell tumours, squamous carcinoma arising within a dermoid, struma ovarii malignum and lymphomas.
Undifferentiated gonadal tissue describes the presence of persistent primitive sex cords
containing immature germ cells.
Development of the sex cords causes the genital ridges to enlarge and grow into the mesonephros.
Clumps of mesenchymal cells between the sex cords will become vascularized and give rise to Leydig cells.
stromal testicular tumors: a clinical series of uniformly stage I disease.