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sialic acid |
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sialic acid: see glycoprotein glycoprotein (glī'kōprō`tēn) ..... Click the link for more information. . sialic acid [sī′al·ik ′as·əd] (biochemistry) Any of a family of amino sugars, containing nine or more carbon atoms, that are nitrogen- and oxygen-substituted acyl derivatives of neuraminic acid; as components of lipids, polysaccharides, and mucoproteins, they are widely distributed in bacteria and in animal tissues. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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As far as we know, 1 of the main blocks to efficient human-to-human transmission of influenza A (H5N1) is the virus's current preference for specific sialic acid receptors. Previous studies have found that beta-amyloid attacks brain cells by attaching to sialic acid molecules that are abundant on the cells' surfaces. The HA protein mediates virus binding to sialic acid (SA)--containing host cell surface molecules and promotes the release of viral ribonucleoprotein complexes through membrane fusion. |
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