When they told me I had Sick Sinus Syndrome
, I was still allowed to work as a firefighter," he said.
AV block and changes in pacing mode during long-term follow-up of 399 consecutive patients with sick sinus syndrome
treated with an AAI/AAIR pacemaker.
TABLE 1 Patient, anaesthetic, ECT and pacemaker details, and concomitant cardiac medications Patient Gender Age (y) Treatments Anaesthetic 1 F 86 26 thio/sux 2 M 81 12 thio/sux 3 M 72 8 thio/sux 4 F 78 12 thio/sux 5 F 72 12 thio/sux 21 prop/sux 6 F 83 17 thio/sux 7 F 89 16 thio/sux 8 F 87 6 thio/sux 9 F 87 8 prop/sux 10 M 80 9 thio/sux Patient Pacemaker Reason Medications 1 DDD tachy-brady syndrome amiodarone atenolol 2 DDDR sick sinus syndrome
diltiazem 3 DDDR syncope none 4 DDDR heart block perindopril 5 DDDR bradycardia atenolol amlodipine 6 VVI sick sinus syndrome
amiodarone digoxin 7 DDDR heart block metoprolol 8 DDDR sick sinus syndrome
none 9 DDDR sick sinus syndrome
frusemide 10 DDD heart block none thio/sux=tmopentone/suxametnomum.
A VVI (ventricular ventricular inhibited) pacemaker had been implanted for treatment of sick sinus syndrome
9 years earlier.
patients without a pacemaker who have sick sinus syndrome
, 2nd or 3rd degree AV block or bradycardic-related syncope) were excluded from the main PLATO study evaluating the safety and efficacy of ticagrelor.
We are committed to turning discoveries such as this, as well as our recent findings in ovarian cancer and sick sinus syndrome
, and our future discoveries, into real benefit for patients," Dr.
Therefore, we concluded that the patient also has concomitant sick sinus syndrome
and we decided to implant a pacemaker.
NICE advises in its latest guidance that up to 90 per cent of all pacemakers implanted to treat sick sinus syndrome
and atrioventricular block - the two primary causes of bradycardia - should be dual-chamber devices, which deliver electrical impulses to both the right atrium and the right ventricle.
GlobalData's clinical trial report, Sick Sinus Syndrome
Global Clinical Trials Review, H2, 2011 provides data on the Sick Sinus Syndrome
clinical trial scenario.