siderophore


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siderophore

[′sid·ə·rə‚fȯr]
(biochemistry)
A molecular receptor that binds and transports iron.
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Some or all isolates of the major CGs associated with community-acquired invasive infections (CG23, CG86, CG375, and CG380) harbored the 2 well-recognized virulence factors iucABCDiutA (aerobactin syndic sis) and rmpA (the positive regulator of mucoid phenotype) in addition to the yersiniabactin siderophore cluster and (except for CG23) the 2-component system kvgAS.
9, 2014 /PRNewswire/ -- S-649266, an investigational parenteral siderophore cephalosporin, exhibits marked potency against Gram-negative bacteria, including multidrug-resistant (MDR) pathogens, in pre-clinical studies.
Pistillarin, as a rare cate cholate siderophore, was found in several macro fungi and marine species such as Penicillium bilaii when grown in relatively high iron environments (Capon et al.
Siderophore production by ECM fungi has been reported for mycelia and ECM tips of a number of species (Machuca et al.
double dagger]) The Siderophore Receptor/Porin proteins-based vaccine (SRP Vaccine) is available in the United States for use under a conditional license granted by the United States Department of Agriculture but not approved for use in Canada.
Probiotic bacteria can be antagonistic to pathogens by means of production of antimicrobial substances, such as antibiotics, antimicrobial peptides, or siderophore substances (Sugita et al.
Heavy metal sorption on soil minerals affected by the siderophore desferrioxamine B: the role of Fe (III) (hydr)oxides and dissolved Fe (III).
For instance, Sunda and colleagues, recently discovered that members of the bacterial genus Marinobacter, which live in close contact with phytoplankton that cause harmful algal blooms, produce a novel siderophore that tightly binds iron in the dark.
Bacteria and fungi counter these defenses by producing siderophores, which are proteins that are synthesized and exported to capture iron, with the resulting iron-siderophore complex endocytosed for use (3).
Specifically it may be a siderophore and/or play a role as a bacterial adhesive.
A new natural ingredient that spontaneously binds with the iron part of siderophore forming a radical-anion has been discovered by Bioderm Research.