silent mutation


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Related to silent mutation: genetic code, Nonsense mutation

silent mutation

[′sī·lənt myü′tā·shən]
(genetics)
A mutation that does not result in amino acid sequence change.
References in periodicals archive ?
The silent mutations 42 (a [right arrow] g) and 138 (c [right arrow] t) were linked with 240 (S/P) dimorphism: 42a and 138c were linked with S240, while 42g and 138t were linked with P240.
It should be noted that 80% of the nucleotide changes in structural regions are transitions (T [left and right arrow] C) and 75% are silent mutations.
Thirty-nine of 43 W-Beijing strains carried an additional and identical mutation in a second putative gene of the mutT family, mutT2, and an identical silent mutation in ogt.
Additionally, rare inactivating variants (TPMT*3B, *3D, *4, *5, *6, *7, and *8) as well as some intronic and silent mutations have been reported, although mostly in single individuals (16, 24, 27) (Fig.
We excluded 14 polymorphisms, 4 silent mutations, and 49 variants detected in introns or untranslated regions.
To investigate whether silent mutations play a role, Gottesman and his colleagues worked with different varieties of the gene called MDR1, which makes P-glycoprotein.
In the F gene, an amino acid change occurred in the initiation codon from Met to Val in PDV/3541UK, compared with the other viruses, and silent mutations occurred at codons 20, 22, 51, 156, 198, 440, and 528.
Again, all 10 polymorphic sites in sequences of lineage 1 strains corresponded to the silent mutations only.
Mutation scanning of LDLR in the whole population: severe, moderate and silent mutations, paucimorphisms and cholesterol level.
Eleven sequence variants in Nramp1 mRNA were obtained from three Salmonella-resistant and three Salmonella-susceptible chicken lines; almost all (10) resulted in silent mutations or conservative changes (to amino acids with similar physical properties) that were detected both in resistant and susceptible chicken lines, while only one sequence variant resulted in a non-conservative substitution of a positively charged residue (Arg223 by a polar residue ([Gln.