skin test

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skin test

[′skin ‚test]
(immunology)
A procedure for evaluating immunity status involving the introduction of a reagent into or under the skin.
References in periodicals archive ?
In a randomized double-blind manner, skin-test sites on 1 arm were covered with 1 mL of placebo cream (Aqueous cream BP, Sandoz, Bordon, Hants, UK) and the skin-test sites on the contralateral arm were covered with zinc sulfate (2) dissolved in aqueous cream to a concentration of 1% elemental zinc.
Control TB skin-test areas to which placebo cream had been applied yielded significantly smaller reactions in persons with lower concentrations of plasma zinc (p = 0.
Studies have been based on a variety of control antigen preparations and skin-test administration and methods for reading test results.
Mumps skin-test antigen has been available for a longer time; lack of response to mumps antigen in HIV-Infected persons has been associated with risk for TB (19), but some patients who have lost PPD reactivity with progression of HIV disease may still react to mumps (24).
There was a marked increase in the number and the rate of tuberculin skin-test conversions among Hospital A employees in 1990 (Figure).
Among the 38 Ward W employees who worked between June 1 and October 1, 1990, those who were working while Patient A was hospitalized had an increased risk for skin-test conversion (43% [12 of 28] vs 0% [0 of 9]; relative risk undefined; P=.
Risk factors for tuberculin skin-test conversion are described in the Table.
The finding that groundskeepers and not animal handlers were associated with a higher risk of tuberculin skin-test conversion was unexpected.
Chest radiographic examinations were performed on all residents, regardless of skin-test status.
Although no information on previous skin-test status was available for the residents, the temporal and spatial clustering of these cases strongly suggests transmission of TB within the facility.
In March 1990, MCHD personnel returned for follow-up skin testing of 70 persons who were previously skin-test negative and were still present in the facility.
Although no additional cases of clinical TB were identified, the investigation identified a total of 31 skin-test positive persons and a documented skin-test conversion rate of 22% (15/69 tested).