spherocyte


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Related to spherocyte: spherocytosis, target cell

spherocyte

[′sfir·ə‚sīt]
(pathology)
A spherical red blood cell.
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9 Platelets * * * Mean Platelet Volume * * * Neutrophils 7 29 58 Bands 54 50 35 Lymphocytes 10 9 5 Monocytes 7 0 2 Metamyelocyte 12 9 0 Myelocyte 8 2 0 Promyelocyte 2 1 0 Nucleated Red Blood Cells 2 0 2 Polychromasia present [dagger] [dagger] Poikilocytosis present [dagger] present Anisocytosis present [dagger] present Microcytes present [dagger] [dagger] Spherocytes present [dagger] [dagger] Mega-thrombocytes present present [dagger] Absolute Neutrophils 3.
It is well known that erythrocytes change into spherocytes by a substantial loss of membrane surface through vesiculation and MV generation.
In the presence of a large number of spherocytes in the peripheral blood film, a major alternative differential diagnosis was autoimmune haemolysis (which can mimic HS).
While hospitalized, the dog had mild anemia without spherocytes, moderate to severe thrombocytopenia with large platelets, moderate leukocytosis with a left shift, a moderate hypokalemia, a mild hypoglycemia, and hypoproteinemia.
Red blood cell morphology was suggestive of a microangiopathic process: microscopic examination indicated that five of the eight infants had mild to moderate (1+ to 2+) hemolysis characterized by the presence of microcytes, burr cells, spherocytes, and bizarre fragments.
echinocytic RBCs, spherocytes, and necrobiotic leucocytes).
Medical conditions such as microcytic anemia, sickle cell anemia, presence of spherocytes and rouleaux, rheumatoid arthritis, chronic infections, Hodgkin's disease, and multiple myeloma affect results.
Peripheral blood smear showed, Howell jolly bodies, target cells and spherocytes.
WBC Toxic granulations 28 Dohle bodies 5 Vacuolations 38 Smudge cells 32 Clefted lymphocytes 10 Hairy projections 2 Auer rods 2 RBC Anisocytosis 54 Poikilocytosis 31 Microcytosis 7 Macrocytosis 2 Hypochromasia 3 Polychromasia 35 Echinocytes (burr cells) 19 Dacrocytes (teardrops) 16 Spherocytes 6 Target cells 2 Acanthocytes 1 Ovalocytes 28 Schistocytes 5 Stomatocytes 2 Howell-Jolly bodies 1 Basophilic stipplings 5 Platelet Clumped platelets 3 Platelet satellitosis 5 Large platelets 8 Giant platelets 8 Overall Cell Morphology Code Concordance, Overall Type % Concordance, % WBC Toxic granulations 78.
The peripheral blood smear was without schistocytes, spherocytes, or atypical cells.