start codon


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start codon

[¦stärt ′kō‚dän]
(genetics)
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Vitamin D receptor start codon polymorphism (FokI) is related to bone mineral density in healthy adolescent boys.
The T/C polymorphism in the first of two start codons (ATG) at the translation initiation site of the VDR gene was detected by restriction fragment length polymorphism analysis using the endonuclease FokI.
While both evidence the general rise in A's and decline in G's near the start codon, each lacks evidence of SD sequences.
Thus when activated by DNA-binding proteins, the enhancer-promoter interaction is the control switch that initiates transcription by signaling the RNA polymerase to bind to the promoter and start codon ATG.
Given that AUG sequences occur randomly throughout a given mRNA, could one of these sequences act as a start codon if positioned at or near the 5' terminus of a message, and how commonly are AUG sequences found in such a position?
dagger]) Assuming the third AUG of ORF2 is the start codon.
DO: Give each student group one START codon bead (methionine).
Exon 0 has three start codons, at -272, -216, and -87, and the one at -87 seems the most likely to become an actual start codon in the type 2 transcript because its sequence connected with the exact open reading frame and the sequence surrounding the start codon (TAAACCGCGATGG) approximates to the consensus sequence (GCCGCCG/ACCAUGG) derived by Kozak (26) more closely than do the corresponding sequences of the former two start codons.
Promoters--Add additional noncoding letters before the start codon.
If the DNA strip was taped in with its start codon adjacent to the SP6 side of the plasmid, the fragments should be 59 bp and 3607 bp.
The start codon for the PB1 gene is located at positions 25 to 27, while the stop codon is at positions 2296 to 2298, yielding a PB1 protein with 757 residues (16,17).
A long ORF is observed from the first methionine start codon at 78-80 to a stop codon at nt 5,142-5,144.