sulfanilamide


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sulfanilamide

[‚səl·fə′nil·ə‚mīd]
(pharmacology)
C6H8O2N2S White crystals slightly soluble in water, soluble in alcohol and most sulfa drugs, but less effective and more toxic than its derivatives.
References in periodicals archive ?
This version of that story provides more details about the discovery of sulfanilamide as the drug's active ingredient and the implications of that fact for the economics of pharmaceutical sales and marketing.
Sulfa drugs or sulfanilamides are inexpensive, yet effective
This approach came under attack in the mid-1930s, after several hundred people, including many children, died after ingesting a sulfanilamide antibiotic preparation that included diethylene glycol--a known poison.
Artemisinin is the most effective antimalarial medicine following chloroquine, pyrimethamine, primaquine and sulfanilamide (4), especially in the treatment of cerebral malaria and chloroquine-resistant malaria with the characteristics of promptness and low toxicity (5).
The synthesis of sulfapyridine and sulfanilamide was demonstrated.
1) Landmark developments in pharmaceutical marketing include the public health catastrophe of some 100 deaths from adulterated elixir sulfanilamide medication that led to the passage of the 1938 U.
Throughout the twentieth century a variety of legislative and regulatory systems were implemented, often in response to drug disasters such as thalidomide (a treatment for morning sickness in pregnancy) and to a lesser extent Elixir Sulfanilamide (an antibiotic) (Geiling & Cannon, 1938) and Stalinon (to treat boils) ('Stalinon': a therapeutic disaster, 1958).
Each hemolymph sample comprised ten 4th-instar larvae, totaling 5 [micro]L, and transferred to Eppendorf tubes containing 55 [micro]L of sulfanilamide (1%) in [H.
Photo allergens After radiation Tetrachloro salicylanilide + Chlorhexidine + Triclosan + Methylcoumarin + Musk ambrette + Thiourea + Isoamyl p-methoxycinnamate + Ethylhexyl p-methoxycinnamate + Benzophenone 4 + Oxybenzone + 4-tert-butyl-4'-methoxy-dibenzoylmethane + Benzydamine + Sulfanilamide + Chlorpromazine + Promethazine + Hydrochlorothiazide + Carbamazepine + Piroxicam + Lichen acid mix + P-aminobenzoic acid + + = positive irradiated photo-epicutaneous test