sulfapyridine


Also found in: Dictionary, Thesaurus, Medical, Wikipedia.
Related to sulfapyridine: sulfadiazine, sulfathiazole

sulfapyridine

[¦səl·fə′pir·ə‚dēn]
(pharmacology)
C11H11N3O2S A sulfonamide formerly used for the treatment of various infections but found to be too toxic for general use; now employed only as a suppressant for dermatitis herpetiformis.
References in periodicals archive ?
Figure 3 shows the comparison between: i) sulfapyridine and sulfadiazine (difference in one nitrogen atom in the heterocyclic moiety), ii) sulfadiazine and sulfisomidine (difference in two methyl groups and in the position of the two nitrogen atoms in the heterocyclic moiety), and iii) sulfamethizole and sulfamethoxazole (difference in one nitrogen atom and the change of a sulfur atom by oxygen atom in the heterocyclic moiety).
Sulphasalazine is separated into sulfapyridine and 5-acetyl salicylic acid after oral administration, and sulfapyridine acetylation is catalyzed by the N-acetyltransferase-2 enzyme in the liver.
weight-bearing joints Isoniazid No adverse effects reported Nalidixic Acid Only in infants with G6PD deficiency Nitrofurantoin Only in infants with G6PD deficiency Sulfapyridine Avoid in infants with G6PD deficiency, and in ill, stressed, or premature infants Sulfisoxazole Avoid in infants with G6PD deficiency, and in ill, stressed, or premature infants Tetracycline Potential for yellow staining of unerupted teeth Antibiotic Recommendation Chloramphenicol Unknown effect on nursing infant, but may be of concern Metronidazole Unknown effect on nursing infant, but may be of concern.
Experimental Rocky Mountain spotted fever and epidemic typhus treated with prontosil or sulfapyridine.
Sulfones such as dapsone sulfapyridine or sulphasalazine rapidly suppress the symptoms of DH.