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sympathomimetic drug

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sympathomimetic drug (sĭmpăth'ōmĭmĕt`ĭk), any of a group of substances whose actions resemble the response of stimulated sympathetic nerves (see nervous system nervous system, network of specialized tissue that controls actions and reactions of the body and its adjustment to the environment. Virtually all members of the animal kingdom have at least a rudimentary nervous system.
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). These drugs include epinephrine epinephrine , hormone important to the body's metabolism, also known as adrenaline. Epinephrine, a catecholamine, together with norepinephrine, is secreted principally by the medulla of the adrenal gland.
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 and other catecholamines catecholamine , any of several compounds occurring naturally in the body that serve as hormones or as neutrotransmitters in the sympathetic nervous system. The catecholamines include such compounds as epinephrine, or adrenaline, norepinephrine, and dopamine.
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 that are naturally produced in the body, and chemically similar substances such as ephedrine ephedrine , drug derived from plants of the genus Ephedra (see Pinophyta), most commonly used to prevent mild or moderate attacks of bronchial asthma.
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. Sympathomimetic drugs excite the central nervous system and heart and affect the diameter of blood vessels. They are used as decongestants and to alleviate bronchial asthma asthma , chronic inflammatory respiratory disease characterized by periodic attacks of wheezing, shortness of breath, and a tight feeling in the chest. A cough producing sticky mucus is symptomatic.
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. Because they inhibit the production of the body substance histamine histamine , organic compound derived in the body from the amino acid histidine by the removal of a carboxyl group (COOH). Although found in many plant and animal tissues, histamine is specifically important in human physiology because it is one of the chemicals
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, they are prescribed for allergic conditions along with antihistamines antihistamine , any one of a group of compounds having various chemical structures and characterized by the ability to antagonize the effects of histamine. Their principal use in medicine is in the control of allergies such as hay fever and hives.
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Unlike sympathomimetic drugs and ephedrine, however, green tea extracts do not increase heart rate and are not associated with adverse cardiovascular effects.
Ephedrine and other sympathomimetic drugs (eg, cocaine, methamphetamine) are derived from phenylethylamine.
Hardman JG, Limbird LE: Catecholamines, sympathomimetic drugs, and adrenergic receptor antagonists.
 
 
 
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