The diagnosis should be considered in growth-restricted babies with cutaneous 3-4 syndactyly
and other suggestive features.
has to be operated in stages within 1-2 years age10 by hand or plastic surgeon in type 3, 4 for functioning of the hand specially thumb and little finger Syndactyly
of feet is usually left alone.
has been observed in dogs, cats, sheep, pigs, and cows [3-8].
SHFM-4 exhibit variable phenotype of split hands and feet malformation with missing phalanges, metacarpals and metatarsals along with or without syndactyly
All the pregnant mice were allowed to give birth to litters which were observed to detect cleft palate, septal defect, limbs ectrodactyly/ syndactyly
and any other sign of abnormality.
In addition, in this close group a high frequency of malformations such as round shaped eyes and orbits, syndactyly
, malformed pinnae, nostrils, lips and jaws was observed, while no such gross abnormalities were seen in the two other experimental groups.
some of the procedures most frequently performed by plastic surgeons at the University of Cape Town Hospital complex Carpal tunnel release Upper limb tendon repair Upper limb nerve and artery repair Syndactyly
and polydactyly correction ORIF hand fracture Cleft palate repair Cleft lip repair Skin graft for burns Flap for lower limb trauma Soft-tissue reconstruction/repair of facial trauma ORIF mandible Nasal fracture repair ORIF Le Fort fracture Prominent ear correction Breast reduction Breast reconstruction (implant or flap) Scar revision and contracture release Fat grafting Free flap for head and neck reconstruction Excision and reconstruction of skin cancers/other skin lesions Flap coverage of pressure sore ORIF = open reduction internal fixation.
The baby was also found to have a narrow thorax, short fingers with postaxial polydactyly in both upper limbs and right lower limb, with syndactyly
in right upper and lower limb (figures 1,2,3).
Findings on Dilation and Evacuation (D&E) Examination Suspicious for Specific Genetic Abnormality Genetic Abnormality Finding on D&E Turner sydrome Fetal hydrops, prominent dorsal edema of (monosomy X) hands and feet, aortic coarctation Trisomy 18 Overlapping fingers, rocker-bottom feet, polydactyly Trisomy 13 Severe craniofacial anomalies, holoprosencephaly, midline cleft lip, abnormal skull base, polydactyly, splenopancreatic fusion, heart defects Trisomy 21 Wide space between first and second toes, clinodactyly, single palmar crease, heart defects, duodenal atresia Triploidy 3-4 syndactyly
Although complete duplication of an entire digit can occur, central polydactyly is often hidden within a syndactyly
and referred to as synpolydactyly.
Other features that can be associated with Klippel-Trenaunay-Weber syndrome are polydactyly , syndactyly
, seizures and hemimegalencephaly , spina bifida, lymphatic obstruction, chronic venous insufficiency, limb ulceration, and thromboembolism .
Physical examination revealed short stature and an incision scar with yellow-greenish purulent material at a recent surgical site on the right leg, pes equinovalgus, right foot oligodactyly, syndactyly
between the third and fourth fingers, and oligodactyly as a bifid digit on the left foot.