Functional characterization of GIu298Asp mutant human endothelial nitric oxide synthase
purified from a yeast expression system.
gene sequence: a new tool for phylogenetic analysis and identification of Ehrlichia.
Studies by other scientists suggested that the sucrose synthase
enzyme - which appeared to break sucrose down so that it could be metabolized by the plant-was more active in immature, rapidly growing sugarcane stems.
com) discovers and develops next-generation pain therapeutics focused on its first-in-class selective inhibitors of neuronal nitric oxide synthase
(nNOS), an enzyme involved in modulating pain and central nervous system neuronal sensitization.
In mice genetically blocked from making fatty acid synthase
in fat cells, Lodhi and his colleagues noticed that the animals' white fat was transformed into tissue that resembled brown fat.
It is a small molecule having a molecular weight of 30 Daltons, which is synthesized, via L-arginine oxidation, by a family of nitric oxide synthase
(NOS) enzymes (2) in which three isoforms have been identified: two constitutive, the neuronal NOS (nNOS, NOS-1) and endothelial (eNOS, NOS-3), and one inducible NOS (iNOS, NOS-2).
In particular, the hps promoter, which in its native state drives the expression of 3-hexulose-6-phosphate synthase
, was found to be useful for directing expression of heterolgous coding regions (e.
rickettsii were detected in Haemaphysalis ticks by polymerase chain reaction analysis of the citrate synthase
(gltA) gene, 16S rRNA, and ompA genes (6).
Hiroyasu Itoh at Hamamatsu Photonics in Tsukuba, Japan, and his colleagues have found a way to use the same enzyme, ATP synthase
, to power nanoscale devices.
In the present study we investigated whether NO inhibition was related to phosphorylation of endothelial nitric oxide synthase
The pellets were resuspended in homogenization buffer, and ecNOS activity in the preparation was measured by the conversion of [3H]arginine to [3H]citrulline with use a Nitric Oxide Synthase
Assay Kit (Calbiochem), according to the manufacturer's instructions.
a development-stage pharmaceutical company that is designing and developing next-generation pain therapeutics targeting neuronal nitric oxide synthase
(nNOS), today announced that it has closed a convertible debenture financing in which the convertible debentures are convertible under specified circumstances into existing class B preferred shares for a total of approximately $14 million.