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systemic inflammatory response syndrome

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systemic inflammatory response syndrome [si¦stem·ik in‚flam·ə‚tȯr·ē ri′späns ‚sin‚drōm]
(medicine)
The spectrum of elicited pathophysiologic changes (including blood clotting and changes in metabolism, heart rate, and respiration) resulting from excess production of inflammatory mediators (for example, histamines and leukotrienes), which orchestrate the process of inflammation through various processes.


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These newborns had a higher incidence of neonatal systemic inflammatory response syndrome (SIRS), higher incidence of bronchopulmonary dysplasia (BPD), higher serum concentrations of interleukin (IL)-6 and more evidence of placental inflammation than those with negative cultures.
Two-hundred and thirty-eight patients with systemic inflammatory response syndrome (SIRS) due to severe sepsis or septic shock were randomly assigned to receive, in double-blind fashion, intravenous selenium (as sodium selenite) or placebo for 14 days.
Systemic inflammatory response syndrome after acute myocardial infarction complicated by cardiogenic shock.
 
 
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