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lupus erythematosus
(redirected from systemic lupus erythematosus)

   Also found in: Dictionary/thesaurus, Medical, Acronyms, Wikipedia, Hutchinson 0.27 sec.

lupus erythematosus

Either of two inflammatory autoimmune diseases, both more common in women. In the discoid type, a skin disease, red patches with grayish brown scales appear on the upper cheeks and nose (often in a butterfly pattern), scalp, lips, and/or inner cheeks. Sunlight worsens it. Antimalarial drugs may help. The second type, systemic (disseminated) lupus erythematosus (SLE), may affect any organ or structure, especially the skin (with marks like those of the discoid type), kidneys, heart, nervous system, serous (moisture-forming) membranes (e.g., in synovial joints or lining the abdomen), and lymph nodes, with acute episodes and remissions. Symptoms vary widely. Kidney and central-nervous-system involvement can be life-threatening. Treatment includes pain relief, control of inflammation, and trying to limit damage to vital organs.



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1) For instance, women are five times more likely to develop hypothyroidism, up to nine times more likely to develop systemic lupus erythematosus (SLE), three to four times more likely to develop Graves' disease, three times more likely to develop rheumatoid arthritis and scleroderma, and twice as likely to develop multiple sclerosis.
We report a fatal case of Acanthamoeba encephalitis in a patient from India who was being treated for systemic lupus erythematosus with corticosteroids and methotrexate.
Grossman, a Valley resident and leading lupus researcher, gives a rundown of the disease, sometimes called SLE, for Systemic Lupus Erythematosus.
 
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