Taurocholic Acid

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Related to taurocholate: glycocholate

taurocholic acid

[¦tȯr·ə¦kȯl·ik ′as·əd]
C26H45NO7S A common bile acid with a five-carbon chain; it is the product of the conjugation of taurine with cholic acid; crystallizes from an alcohol ether solution, and decomposes at about 125°C. Also known as cholaic acid; cholytaurine.

Taurocholic Acid


one of the conjugate bile acids; a product of the conjugation of cholic acid with taurine. It is formed in the liver of animals and man and released with bile into the intestine. It participates in fat metabolism, facilitating the emulsifiction of fats and activating the enzyme lipase, thereby promoting the digestion and absorption of fats.

References in periodicals archive ?
Current bench-based, fluorometric enzyme assay protocols require 2 separate punches for measuring the activity of GAA and GLA, because the punch for Pompe assay is extracted in deionized water, whereas the punch for Fabry assay requires 1% sodium taurocholate.
On enrollment, fresh stool sample was taken from each patient for culture (inoculated into tellurite taurocholate gelatin agar, Mackonkey and Shigella-Salmonella agar) and sensitivity test.
Sodium taurocholate reduced the activity of all 3 enzymes at all concentrations tested (see Table 3 in the online Data Supplement).
OATP-B, OATP-D, OATP-E) tended to have substrate affinity toward steroid sulfate, although OATP-E (an Oatp4a1 homolog) also had affinity toward taurocholate.
Briefly, 5 g of each sample was cultured in 100 mL of prereduced brain-heart infusion (BHI) broth supplemented with cefoxitin (10 [micro]g/mL), cycloserine (250 [micro]g/mL), and taurocholate (0.
5 [micro]g/min for 60 min in 140 mM NaCl containing 10mM sodium taurocholate using a Harvard syringe pump.
In the early period after hatching, the bird entero-hepatic circulation is still immature, and this causes the accumulation of taurocholate in ileum (JEANSON & KELLOGG, 1992).
0 gm % sodium taurocholate to the standard (basal) commercial diet and daily feed consumption was recorded.
Merck, Darmstadt, Germany (all substances not specifically attributed to other source), Novartis, Grenzach-Wyhlen, Germany (Liquemin[R]), Sigma, Munchen, Germany (BSA, sodium taurocholate and thiobarbituric acid) and Synopharma, Hamburg, Germany (butylhydroxytoluol).
To the residue we added 15 [micro]L of 120 g/L sodium taurocholate in water.
Cyp7b1 is the hydroxylase involved in taurocholate bile acid synthesis in mice (Russell 1999).
Cyclooxygenase and lipoxygenase metabolism in sodium taurocholate induced acute hemorrhagic pancreatitis in rats.