temperature-sensitive mutant


Also found in: Medical.

temperature-sensitive mutant

[′tem·prə·chər ¦sen·səd·iv ′myüt·ənt]
(genetics)
A mutant gene that is functional at high (low) temperature but is inactivated by lowering (elevating) the temperature.
References in periodicals archive ?
Gubbels said that researchers in his lab obtained a temperature-sensitive mutant of Toxoplasma gondii, which displayed a mobility defect preventing it from host cell invasion.
Temperature-sensitive mutants of mouse hepatitis virus produce a high incidence of demyelination.
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