teratogen


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teratogen

[tə′rad·ə·jən]
(medicine)
An agent causing formation of a congenital anomaly or monstrosity.
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In this study, a small proportion of the mothers had diabetes or they were epileptics on therapy; however, a further study with a larger sample would be required to analyse the impact of various known teratogens on the NTDs in this population.
more than five standard drinks on one occasion (Kvigne 2003), at a point where embryonic or fetal development is particularly vulnerable to teratogens, may also be at risk of giving birth to an alcohol effected child.
With this in mind, meclizine could very well be considered a potential human teratogen.
Studies of alcohol as a teratogen in other species are reviewed in Carrie L.
director of the Motherisk Program, a teratogen information service at the Hospital for Sick Children, Toronto, said that while the identification of these cases in an international database was commendable, he took issue with the conclusion that paroxetine should not be used in pregnancy.
org/) offering expectant moms a one-stop source for finding the latest information about the potential risks of exposure to drugs, chemicals and other harmful agents has been launched by the California Teratogen Information Service (CTIS).
At the Motherisk Program, a teratogen information service at the Hospital for Sick Children in Toronto, we are following the long-term development of children exposed in utero to valproic acid, which we hope will pick up an association with autism, if such a link exists.
After evidence--based counseling, however, these beliefs were nearly completely reversed, and the majority of women decided to continue therapy, reported Lori Bonari, a teratogen information counselor and researcher with Motherisk, the national pregnancy teratology information service at the University of Toronto.
This is because the prenatal teratogen - the substances that cause the abnormalities - act diffusely in the foetal brain, resulting in multiple defects.
In 1973, the two published their finding that alcohol was a teratogen in the British journal Lancet.