tetanospasmin

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tetanospasmin

[‚tet·ən·ō′spaz·mən]
(biochemistry)
A neurotoxin elaborated by the bacterium Clostridium tetani and which is responsible for the manifestations of tetanus.
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Tetanus is diagnosed by clinical signs and history of recent trauma, demonstrating the presence of tetanus toxin in serum, and demonstration of the bacterium in Gram-stained smears, and by anaerobic culture when a wound is apparent.
The key elements in the management of tetanus include neutralization of tetanus toxin, wound debridement, antibiotic therapy, respiratory support and management of spasms and autonomic dysfunction (10).
Clostridium tetani can enter the body through a traumatic wound; the organism matures and produces the tetanus toxin.
Doctors at the European Breast Cancer Conference in Barcelona said the tetanus toxin was being used to develop a vaccine for breast cancer and was now in trials.
But because both DTP and DTaP have been associated with severe (but not life-threatening) local reactions, serologic testing for specific IgG antibody to both diphtheria and tetanus toxin is reasonable (correlates of protection for pertussis are not established).
Few compounds bind to nerve endings as well as tetanus toxin.
Protection against disease is due to the development of neutralizing antibodies to tetanus toxin.
Another three jars contained an orange color mix which "when stored in an anaerobic environment creates tetanus toxin, which once contracted, attacks the central nervous system and causes death," a member of the service risk management at BCIJ explained to HuffPost.