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thalassemia |
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thalassemia [‚thal·ə′sē·mē·ə] (medicine) A hereditary form of hemolytic anemia resulting from a defective synthesis of hemoglobin: thalassemia major is the homozygous state accompanied by clinical illness, and thalassemia minor is the heterozygous state and may not have evident clinical manifestations. Also known as Mediterranean anemia. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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vulnificus infection, including chronic liver disease (30%), chronic renal failure (15%), diabetes mellitus (7%), and thalassemia major (3%). Yersiniae have an impaired iron metabolism, and for this reason, they rarely cause sepsis in patients without iron overload, which is often secondary to alcoholism, asplenia, hemochromatosis, thalassemia major, or tobacco smoking (1). Pegasys and Copegus therapy is additionally contraindicated in women who are pregnant, men whose female partners are pregnant, and patients with hemoglobinopathies (eg, thalassemia major, sickle-cell anemia). |
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