thiazole


Also found in: Dictionary, Wikipedia.
Related to thiazole: thiazole orange

thiazole

[′thī·ə‚zōl]
(organic chemistry)
C3H3NS A colorless to yellowish liquid with a pyridinelike aroma, slightly soluble in water, soluble in alcohol and ether; used as an intermediate for fungicides, dyes, and rubber accelerators.
References in periodicals archive ?
Ghorab, Anti-Breast Cancer Activity of Some Novel 1,2-dihydropyridine, thiophene and thiazole derivatives, Eur.
For example, the given thiazolidenediones definition does not make clear whether non-insulin sensitizing agents with two keto oxygens and a thiazole group are thiazolidenediones.
The Sapphire method is rather similar to the widely used flow cytometric method with thiazole orange, but it is fully automated and fully standardized regarding incubation time and concentration of the fluorescent RNA dye.
Occurrence of some long-chain alkylthiazoles in meat (adapted from Melton, 1999) Thiazole Beef heart Beef Chicken Longissimus breast dorsi 5-Octyl-4-ethyl - (1) tr (2) +++ (5) 5-Nonyl-ethyl + (3) ++ (4) +++ 5-Decyl-4-ethyl - tr ++ 2-Tridecyl-4,5-dimethyl + tr - 2-Tridecyl-4/5-ethyl ++ - - 2-Tetradecyl-4,5-dimethyl + - - 2-Pentadecyl tr tr +++ 2-Pentadecyl-4-methyl +++ ++ ++ 2-Pentadecyl-4/5-ethyl +++ ++ ++ (1) Absent.
Light-up probes: thiazole orange-conjugated peptide nucleic acid for detection of target nucleic acid in homogeneous solution.
Thiophene, thiazole, pyrazole, isoxazole and pyrimidine derivatives isolated and fused being an integral part of DNA and RNA which play an essential role in several biological processes and have considerable chemical and pharmacological importance, particularly, the pyrimidine ring can be found in nucleoside antibiotics, antibacterials, cardio: vascular as well as agro chemical and vetcer products [1] In addition, many of these derivatives were found to possess a variety of pronounced activities such as an anti-inflammatory [2-6], antimalarial [7-9], anti-allergic [10-11], antimicrobial [12-17].
The thiazole ring system is a useful structural moiety found in numerous biologically active molecules.
To test this explanation, we created a small model of the system with an iron ion bound to the four nitrogen atoms of a porphine ring (representing porpyhrin IV), the sulfur of a methylthiolate (representing a cysteine side chain), and a thiazole ring (representing a small model of ritonavir).
Corrosion Inhibition of Mild Steel Using Emulsified Thiazole Adduct in Different Binder Systems.
Several investigators used different methods for evaluating activity of compound against axenic amastigotes such as viability of cell population with a 3-(4-5 dimethylthiazol-2- yl)--2, 5 diphenyl tetrazolium bromide, Thiazole blue (MTT) based method 11,12, determining ornithine decarboxylase activity (8) or using a fluorescent dye like propidium iodide (PI) and fluorescence-activated-cell-sorter (FACS) (13,14).
The thiazole molecule is almost perpendicular to the plane of the saccharinato ligand.
These are transformed to yield heterocyclic compounds that are analogs of the ring systems of pyridine, pyrimidine, thiazole, pterin, and isoalloxazine (Begley, 2006).