thiobarbituric acid


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thiobarbituric acid

[¦thī·ō‚bär·bə′tu̇r·ik ′as·əd]
(organic chemistry)
C6H4N2O2S Malonyl thiourea, the parent compound of the thiobarbiturates; represents barbituric acid in which the oxygen atom of the urea component has been replaced by sulfur.
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11] Products of lipid peroxidation were detected in reaction with thiobarbituric acid, [12] so these products have named as TBA-reactive products.
Generally, effects of oxidation can be evaluated by acid value (AV) representing hydrolytic reactions, peroxide value (PV), conjugated diene and triene acids as indicators of primary oxidation in addition to malonaldehyde (MAD), anisidine value and thiobarbituric acid reactive substances (TBARS) as indices of secondary oxidation products.
Malondialdehyde was measured in serum by using the thiobarbituric acid test based on Valipasha and Sadasivadu's [2] procedure; 1 mL of serum was added to 1 mL of 40% trichloroacetic acid followed by addition of 2 mL of 0.
Thyme oil reduced lipid oxidation as measured by thiobarbituric acid value.
To demonstrate lipid peroxidation in mice liver, extract - sodium nitroprusside (5uM) or ferrous sulphate (10uM) was introduced to produce thiobarbituric acid reactive species (TBARS).
Briefly, 250 [micro]L of tissue or serum homogenate, 500 [micro]L of thiobarbituric acid (TBA) reactant (3.
The aim of this research was to determine levels of thiobarbituric acid reactive substance (TBARS) in blood of pregnant women with pregnancy induced hypertension and to analyze the correlation of TBARS parameters with clinical parameters during pregnancy and delivery in pregnancies with pregnancy induced hypertension.
MDA reacts with deoxyadenosine and deoxyguanosine in DNA, forming DNA MDA and other thiobarbituric acid reactive substances (TBARS) condense with two equivalents of thiobarbituric acid to give a fluorescent red derivative.
Oxidative stress was reduced by lowering of thiobarbituric acid reactive substances by 28.
Estimation of serum MDA was determined by Thiobarbituric Acid Reactive Substances (TBARS) kit, on spectrophotometer.
The quantitative estimation of lipid peroxidation was done by determining the concentration of thiobarbituric acid reactive substance (TBARS) in the brain using the method of Ohkawa et al.