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microangiopathy
(redirected from thrombotic microangiopathy)

   Also found in: Medical, Acronyms 0.01 sec.
microangiopathy [‚mī·krō‚an·jē′äp·ə·thē]
(medicine)
The development of lesions in small blood vessels throughout the body.


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Although the typical pathologic lesions of SLE and TTP both primarily involve arterioles, the characteristic histologic patterns are distinct: inflammation with vasculitis in SLE and platelet-rich thrombi without overt inflammation, termed thrombotic microangiopathy, in TTP.
Renal biopsy obtained later in the course of hospitalization revealed thrombotic microangiopathy with severe, chronic and ongoing involvement of the small arteries and arterioles, consistent with scleroderma.
Thrombotic microangiopathy with glomerular thrombi and atrophy
 
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