Thrombus


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Related to Thrombus: thrombi, mural thrombus

thrombus

[′thräm·bəs]
(medicine)
A blood clot occurring on the wall of a blood vessel where the endothelium is damaged.

Thrombus

 

a clot of blood formed during life.in the lumen of a blood vessel or in the heart. In a broader sense, extravascular clots of blood that form during bleeding, as well as clots of lymph in the lymphatics are also called thrombi.

The formation of a thrombus consists of the following stages: agglutination of platelets, coagulation of fibrinogen, agglutination of red blood cells, and precipitation of plasma proteins. Thrombi may be white, red, laminated, or hyaline. A white thrombus consists of platelets, fibrin, and white blood cells and is formed slowly during rapid blood flow, generally in arteries. A red thrombus, in which red blood cells predominate, forms rapidly during slow blood flow, generally in veins. The most common type of thrombus is the laminated thrombus, which has a layered structure and crimped surface and contains fragments of white and red thrombi. It is attached to the endothelium of a blood vessel, generally that of a vein; this differentiates it from a postmortem thrombus. A hyaline thrombus forms in blood vessels of the capillary bed and consists of a homogenized mass of protein.

A thrombus may be parietal or obstructive. A parietal thrombus forms within the heart in endocarditis and heart disease, in large arteries in atherosclerosis, and in veins in thrombophlebitis. As a parietal thrombus grows, it becomes obstructive, generally in small arteries and veins. A thrombus that grows rapidly into the lumen of a vessel is called progressive, and one that originates in cardiac insufficiency is called congestive. A thrombus that forms in aneurysms is called dilatational; one that is unattached within an atrium is called spherical. A thrombus can dissolve or can grow connective tissue, a process called organization. Thin-walled blood vessels may appear in this tissue (canalization), or calcium salts may be deposited (calcification). A thrombus may cause an embolism or may become purulent, a condition accompanied by a thrombobacterial embolism and leading to sepsis.

V. V. SEROV

References in periodicals archive ?
During the echocardiographic study in the same setting, it was observed that the large, mobile thrombus had disappeared from the right atrium and was found lodged in the right pulmonary artery (Figure-2).
Myxoma was primarily considered to be the diagnosis because of a mobile, pedunculated mass in a normal functioning LV, although, with a low probability, our differential diagnosis included a thrombus (7).
The development of occlusive thrombus within the lumen of coronary artery in the absence of collateral blood vessels most often results in the development of acute ST-segment elevation myocardial infarction (STEMI)2.
The ClotTriever is currently available for treatment of thrombus in the peripheral veins at select centres and the company plans to add more centres as it gains clinical experience.
LA/LAA thrombus was defined as a well-circumscribed echogenic mass with a unique echotexture contrasting with the adjacent myocardium.
Conclusion: Left ventricular thrombus formation is associated with anterior wall myocardial infarction and stroke.
The evolution was slowly improved, he was extubated, and a pulmonary CT angiogram showed multiple bilateral thrombi and a saddle thrombus in the pulmonary artery bifurcation.
Echocardiography showed a large free-floating thrombus in the right atrium, and it extended to the right ventricle and the main pulmonary artery.
Some authors suggest that an inflammatory process surrounding chronic bland thrombus is responsible for associated FDG avidity [1,2,5].
A) Circumflex layered massive organized thrombus in the left main coronary artery (LMCA) covering the ostium of the circumflex (CX) and left anterior descending coronary artery (LAD) (B).
KEY WORDS: Mitral stenosis, Left atrium, Thrombus, Transesophageal echocardiography.