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tophus |
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tophus [′tō·fəs]
(medicine) A localized swelling principally in cartilage and connective tissues in or adjacent to the small joints of the hands and feet; occurs specifically in gout. Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content. |
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No references found | Suspected tophus (deposit or accumulation of uric acid crystals under the skin) Laboratory factors such as ? The hyperintense signal intensity seen on T2W spin-echo images may reflect the high protein content in the amorphous center of the tophus, while the decreased signal intensity may indicate regions of calcification within the tophus, fibrous tissue and crystals, hemosiderin deposition, or proton immobility. Although the rapid decline in his ambulatory status may not be explained completely by the chronicity of tophaceous gout, it does perhaps suggest that the tophus was undergoing a phase of acute inflammation, with cellular infiltration and inflammatory exudate formation, producing pain and resulting in a critical size increase, which was sufficient enough to produce clinical evidence of cord compression. |
tophus |
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