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tophus

   Also found in: Dictionary/thesaurus, Medical, Wikipedia, Hutchinson 0.01 sec.
tophus [′tō·fəs]
(medicine)
A localized swelling principally in cartilage and connective tissues in or adjacent to the small joints of the hands and feet; occurs specifically in gout.


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Tophus (plural tophi): A hard deposit of crystalline uric acid that may appear as a lump just under the skin, particularly around the joints and at the rim of the ear.
The first of four Savient posters presented at the meeting reported on anecdotal findings of gout tophus eradication after 12 weeks of PEG-uricase treatment, and includes both photographic and radiological results.
 
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