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topoisomerases
(redirected from Topoisomerase)

   Also found in: Medical, Wikipedia 0.01 sec.
topoisomerases [¦tä·pō·ī′säm·ə‚rās·əz]
(biochemistry)
Any of a group of enzymes capable of relaxing, unwinding, unpackaging, or changing the degree of supercoiling of deoxyribonucleic acid fiber.


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8), and more recently, the need for such an enzyme has been reiterated by those examining the actions of topoisomerase I inhibitors (9, 10).
9780879698799 Untangling the double helix; DNA entanglement and the action of the DNA topoisomerases.
Resistance is caused mainly by amino acid changes in quinolone resistance-determining regions (QRDRs) of the subunits of DNA topoisomerase IV (topo IV; [parC.
 
 
 
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