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Megacolon
(redirected from toxic megacolon)

   Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.01 sec.
megacolon [′meg·ə‚kō·lən]
(medicine)
Hypertrophy and dilation of the colon associated with prolonged constipation.

Megacolon 

in man, enlargement of part or all of the colon.

Megacolon usually originates with congenital immaturity of the colon’s innervation apparatus. The clinical course of the condition is characterized by persistent constipation beginning in the first years (sometimes in the first months) of life. This, the most common form of megacolon, is called Hirschsprung’s disease. In adults, megacolon may be caused by the presence of mechanical obstructions (tumor, cicatricial stenosis). Treatment is surgical.



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1) Symptoms of CDI range from mild diarrhea to colitis, toxic megacolon, colon perforation, sepsis, and death.
Complicated CDAD includes hypotension, ileus, toxic megacolon or colonic perforation.
Severe CDAD exists with the occurrence of a paralytic ileus or toxic megacolon that may lead to decreased stools or even no diarrhoea being produced.
 
 
 
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