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transmethylation |
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transmethylation [¦tranz‚meth·ə′lā·shən] (biochemistry) A metabolic reaction in which a methyl group is transferred from one compound to another; methionine and choline are important donors of methyl groups. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Folate deficiency may influence urinary creatinine concentrations because the synthesis of creatine, the precursor of creatinine, accounts for approximately 75% of folate- and S-adenosylmethionine (SAM)-dependent transmethylation reactions (Figure 2, reaction 6; Mudd et al. Although this association had not been previously reported, it is not surprising considering that the formation of creatine from methylation of guanidinoacetate accounts for approximately 75% of all folate-dependent transmethylation reactions (Mudd and Poole 1975) and that creatine is the direct precursor of creatinine. Following transmethylation, with use of BF3/methanol, the fatty acid profile was determined by capillary gas-liquid chromatography. |
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