Table 19: Incidence of EPS Compared to Placebo in the Adjunctive Therapy Bipolar Depression Studies Adverse Event Term Placebo LATUDA 20 to (N=334) 120 mg/day (%) (N=360)(%) All EPS events 13 24 Ail EPS events, 9 14 excluding Akathisia/Restlessness Akathisia 5 11 Dystonia* 1 1 Parkinsonism** 8 13 Restlessness 1 4 Note: Figures rounded to the nearest integer *Dystonia includes adverse event terms: dystonia, oculogyric crisis, oromandibular dystonia, tongue spasm, torticollis, and trismus
**Parkinsonism includes adverse event terms: bradykinesia, cogwheel rigidity, drooling, extrapyramidal disorder, glabellar reflex abnormal, hypokinesia, muscle rigidity, parkinsonism, psychomotor retardation, and tremor
Ansefalit ve menenjit trismus
ve yaygin tonus artisi ile basvurabilir.
In a previous study, the treatment regimen was standardized with patients of OSMF with trismus
be treated by 1.
A 27-year-old Malaysian woman presented with a 2-month history of progressive right cheek swelling, right orbital swelling, double vision, and associated fever and trismus
Examination of the oral cavity was complicated by trismus
, however no obvious tonsillar enlargement, erythema or exudate was recorded.
Stretching exercises during and post therapy can alleviate the effects of trismus
group sex period, d Symptoms 1/A 60/M 7 Fever, myalgia, malaise 2/A 52/M 6 Fever, myalgia, malaise, periorbital swelling, leg swelling 3/A 57/M 14 Myalgia, malaise, trismus
, tremor 4/A 57/F 8 Fever, chills, dyspnea, myalgia, malaise, trismus
, tremor, periorbital swelling 5/A 62/M 15 Fever, myalgia, malaise 6/B 52/M 8 Fever 7/B 57/M 7 Fever, myalgia, leg swelling, periorbital swelling, skin rash 8/B 47/M 8 Fever, myalgia Acute-phase titer ([dagger]) Patient Eosinophils, T.
Initial symptoms include odynophagia limiting oral intake, trismus
, change in voice and systemic symptoms of infection.
Other presenting signs included trismus
, facial hypoesthesia, cranial nerve VI palsy, and vocal fold paralysis (table 1).
Although OSF with trismus
may result in expected difficult intubation, unanticipated difficult intubation has been reported in a patient with OSF even without trismus
Other reported signs and symptoms include trismus
, neck stiffness, bruising, globus, dyspnoea and odynophagia (2).
is a spasm of the masticatory muscle caused by a disturbance in the trigeminal nerve that causes difficulty in opening the mouth.